Browsing Fakultät für Biologie und Psychologie (inkl. GAUSS) by Referee "Liebl, Wolfgang Prof. Dr."
Now showing items 1-20 of 36
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Aktivität endogener Retroviren in Tumorgeweben von Primaten
(2009-09-14)The human endogenous retroviruses of the family K (HERV-K) is an evolutionary young group of retroviral sequences. In comparison with other endogenous retroviruses, some HERV-K proviruses ... -
Analyse des Transkriptionsfaktors TGA2.1 aus Nicotiana tabacum
(2002-04-02)The thesis explores the possible function of the plant transcription factor TGA2.1. For this purpose genetically modified plants were generated in which a) TGA2.1 was ectopically overexpressed ... -
Auswirkungen der Deletion membranständiger Dehydrogenasen auf Gluconobacter oxydans DSM 7145
(2009-11-06)Gluconobacter oxydans is one of the most important organisms in industrial biotechnology because of its ability to incompletely oxidize various sugars, sugar alcohols and sugar acids. The ... -
Blue light-dependent development of the filamentous fungus Aspergillus nidulans
(2007-11-22)Numerous studies have revealed that fungal development and the production of secondary metabolites are linked although the molecular mechanisms are yet unknown. Light seems to be one of the ... -
Characterization of neuronal SNAREs and interacting proteins
(2006-03-20)This work centered on the SNARE proteins syntaxin 1, SNAP-25, and synaptobrevin 2, which drive the discharge of neurotransmitters from synaptic vesicles. A relatively simple scenario for ... -
Charakterisierung von funktionellen Oberflächenstrukturen des Hepatitis-B-Virus Nukleokapsids
(2005-12-28)During hepatitis B virus (HBV) morphogenesis the transmembrane large envelope protein (L protein) probably directly interacts with mature cytosolic nucleocapsids. The shell of the capsid ... -
Congenital Disorders of Glycosylation IIj (CDG-IIj): Identifizierung eines Defekts der COG6-Untereinheit des Conserved Oligomeric Golgi-Komplexes
(2010-09-16)`Congenital Disorders of Glycosylation` (CDG) are a rapidly expanding group of so far 23 autosomal recessive multisystemic disorders associated with deficiencies in the biosynthesis of ... -
DAHP Synthasen aus Pilzen
(2002-07-09)The first step of the biosynthesis of the aromatic amino acids is the condensation of erythrose-4-phosphate and phosphoenolpyruvate to 3-deoxy-D-arabino-heptuloso-nate 7-phosphate. This ... -
Genome sequence of <i>Escherichia coli</i> 536: insights into uropathogenicity through comparison with genomes of <i>Escherichia coli</i> MG1655, CFT073, and EDL933
(2006-02-09)Uropathogenic Escherichia coli (UPEC) strain 536 (O6:K15:H31) is one of the model organisms of extraintestinal pathogenic E. coli. To analyze this strain s genetic basis of ... -
Herstellung und Charakterisierung monoklonaler Antikörper gegen die Anaphylatoxin-Rezeptoren
(2008-01-29)Anaphylatoxins are potent pro-inflammatory mediators that induce their biological effects through high affinity binding to specific cellular receptors. Due to controversial evidence in the ... -
Identification and characterization of Campylobacter jejuni factors relevant for the infection process
(2007-10-09)Campylobacter jejuni is the most frequent bacterial cause of foodborne-illness in the developed world including Germany, where the reported number is 60,000 cases in a year. Despite the ... -
Identification and Characterization of Microbial Key Functions in Soils of the German Biodiversity Exploratories Representing Different Land Use and Management Types
(2012-05-11)Soil probably harbors the highest microbial species diversity of any environment on Earth and represents a major reservoir of microbial taxonomic, genomic, and metabolic diversity. The most promising approach to gain ... -
Identifizierung und Charakterisierung von Genen und korrespondierenden Genprodukten aus Metagenombanken, die Butanol-Dehydrogenase-Aktivität oder proteolytische Aktivität vermitteln
(2006-07-07)The cultivation-independent assessment and exploitation of the vast microbial diversity by metagenomics offers an almost unlimited resource of new genes, gene products, and biosynthetic ... -
Identifizierung und Charakterisierung von thermostabilen Uracil Glykosylasen von Archaeon Methanobacterium thermoautotrophicum und Bakterium Thermus thermophilus
(2002-05-22)Hydrolytic deamination reactions of cytosine and 5-methylcytosine results in highly mutagenic U/G and T/G mismatches, respectively. These processes are especially pronounced at high ... -
Isolierung von DNA und Konstruktion einer Metagenombank aus dem Sediment des Flusses Leine: partielle Sequenzierung und Annotation des Metagenoms sowie Analyse der mikrobiellen Diversität
(2006-01-17)Isolation of environmental DNA, subsequent construction of metagenomic libraries, or amplification and cloning of 16S rRNA genes, and final sequencing of cloned DNA allow phylogenetic and ... -
Komparative Genomanalyse zur Stammoptimierung produktionsnaher Bacillus-Stämme
(2011-06-30)B. licheniformis DSM13 is a Gram-positive, ubiquitous, endospore forming bacterium that is extensively used for industrial production of exoenzymes as it can secrete high amounts of protein. ... -
Konstruktion eines bakteriellen Systems zum Export von Coenzym B<sub>12</sub>
(2003-11-04)B12 is exclusively synthesized in the cytoplasm of some Bacteria and Archaea. More than 30 different enzymes are involved in the synthesis of this coenzyme. A natural export system for ... -
Localization and Stability of the Transcriptional Activator Gcn4p of Saccharomyces cerevisiae
(2003-02-27)The «general amino acid control« (GAAC) of the yeast Saccharomyces cerevisiae is a well characterized regulatory network which secures a sufficient amino acid supply of the organism. This ... -
Metagenomanalysen von zwei Habitaten mit (hemi-)cellulolytischen mikrobiellen Gemeinschaften
(2010-06-04)The analysis of metagenomes not only can give an insight into the microbial diversity of a habitat, it can also reveal new biocatalysts by screening of metagenomic DNA-libraries. In the ... -
Metagenombasierte Isolierung und biochemische Charakterisierung neuartiger stereospezifischer Lipasen für biokatalytische Anwendungen
(2007-08-31)The technique of cloning DNA from a certain habitate, the so called metagenome contributed in the last years successfully to the accession of the genetic potential of all present ...