Dokumente GZMB - Göttinger Zentrum für molekulare Biowissenschaften nach Titel
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The rhizosphere effects of <i>Fagus sylvatica</i> L. and <i>Fraxinus excelsior</i> L. saplings on greenhouse gas fluxes between soil and atmosphere
(2012-12-07)Tree species influence the soil through stemflow and throughfall water, leaf litter and the root system. Little is known about the effects of tree roots on the C and N dynamics of the soil and the gas exchange with ...
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The role of Lissencephaly-1 protein in male germ cell differentiation
(2009-07-24)In the present study the function of Lissencephaly-1 protein in male germ cell differentiation was analysed. A gene trap mouse model (L39) in which a gene trap vector had integrated in intron 2 of Lis1 gene resulted in ... -
The Role of the HECT-Type Ubiquitin Ligases WWP1 and WWP2 in Nerve Cell Development and Function
(2012-03-15)Posttranscriptional modification of proteins through the ubiquitin pathway has recently emerged as an essential regulatory mechanism controlling neuronal development and function. WW domain-containing protein-1 and -2 ... -
The signal transduction of synapse formation and it's failure in Rett syndrome
(2017-04-26)The mechanistic target of rapamycin (mTOR) perceives and integrates various extracellular and intracellular signals and regulates cellular growth and homeostasis. The evolutionary conserved serine/threonine kinase can form ... -
Transcriptional control in the context of primary neurogenesis
(2006-09-18)The Myc/Max/Mad network of bHLH-Zip transcription factors plays an essential role in a variety of cellular processes including proliferation, differentiation and apoptosis. Mxi1, a Mad family member, was previously ... -
Untersuchungen zur Funktion der Gene MPH1 und MMS2 aus Saccharomyces cerevisiae bei der fehlerfreien Umgehung von replikationsarretierenden DNA-Schäden
(2010-02-25)in vivo error free bypass of replication blocking lesions is done by at least two distinct processes: homologous recombination via sister chromatid interaction (SCI) and post replicative repair (PRR). Additionally PRR is ... -
Untersuchungen zur Wirksamkeit von Dacarbazin und Temozolomid bei der Behandlung des kutanen Melanoms in Assoziation mit DNA-Reparatur
(2010-02-09)The aim of this study was to identify individual host markers for hematologic side effects and treatment efficacy of dacarbazine or temozolomide in melanoma treatment. Such markers could facilitate the decision for or ...