Dokumente Medizin nach Titel
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Ultraschall-gesteuerte Freisetzung von an Nanopartikeln gebundenem Nimodipin und deren Anwendung zur Therapie von experimentell erzeugten Vasospasmen an der Chorioallantoismembran des embryonalen Eis
(2022-12-05)Nimodipine prevents cerebral vasospasm and improves functional outcome after aneurysmal subarachnoid hemorrhage (aSAH). The beneficial effect is limited by low oral bioavailability of nimodipine, which resulted in an increasing ... -
Ultraschallgestütze Bohrloch-Biopsien bei intraaxialen Hirnpathologien
(2018-07-31)Intraoperative ultrasound is able to display dynamic processes intraoperatively in real-time fashion. So in case of burr-hole biopsies it seems to be an interesting option for neurosurgeons. Value and complications of this ... -
Ultrastructural characterization of human thigh lymphatic collectors
(2018-01-04)Lymphedema is a condition that affects millions of patients worldwide. Most of the research has been performed on animals, while the cellular and molecular characteristics of human lymphatic collectors have been largely ... -
Umfrage zum Stand der endodontischen Behandlung in Deutschland
(2016-10-10)Endodontics has developed considerably over the last years, but there are only few studies on the materials and methods preferred by German dentists for root canal treatment and respective developments over the years. The ... -
Der Umgang mit individuellen Befunden bei der Biobank-Forschung
(2016-11-09)During the last decades biomedical science has developed more rapidly than ever. Especially biogenetical and information technologies have contributed to new dimensions in research that were inconceivable in the past. Data ... -
Der Umgang von Gesundheits- und Krankenpflegeschülern mit Benzodiazepinen und Z-Substanzen im Krankenhaus – Ergebnisse von Gruppendiskussionen
(2021-10-01)The use of benzodiazepines and Z-drugs for difficulties in falling asleep and staying asleep at the hospital increases the risk for inappropriate sedation, falls and fractures. The issue of the proper use of these ... -
Uncovering triggers of colonization in brain metastasis
(2017-04-26)Brain metastases (BM) are frequent in cancer patients and are associated with poor prognosis. The incidence of BM is increasing mainly due to an improved control of primary tumors and an increased median survival of the ... -
Understanding Secretory MVB Trafficking for the Release of Small Extracellular Vesicles
(2021-04-16)The release of small extracellular vesicles (sEVs) from multivesicular bodies (MVBs) represents an integral part of intercellular communication during development, homeostasis and disease. While secretory MVBs are ... -
Der unkomplizierte Harnwegsinfekt in der ambulanten Versorgung
(2021-06-18)Increasing resistance rates of uropathogenic germs require a rational use of antibiotics in the treatment of uncomplicated urinary tract infections. In addition to antibiotic treatment strategies, symptomatic therapy options ... -
Unravelling epigenetic mechanisms of CAF-chemotherapy resistance in mammary carcinoma
(2020-01-29)Triple negative breast cancer (TNBC) is one of the most challenging cancers to treat as, despite the initial response to chemotherapy, relapse occurs frequently. In this project, we focused on the mechanisms that allow ... -
Unterkieferrekonstruktion durch kontrollierte rh-BMP-2-Freisetzung mit Hilfe von präformierten Trägern aus Polylaktid und Kollagen
(2009-11-12)The aim of this study was to show that controlled release of recombinant human bone morphogenetic protein 2 (rh-BMP-2) trans a slow release polylactic acid carrier can repair critical size defects in the rat mandible. ... -
Unterschiede im intensivmedizinischen Management bei akuter aneurysmatischer Subarachnoidalblutung: eine Umfragestudie
(2021-10-26)Objective: The aim of this study is to provide an overview of the management of acute aneurysmal subarachnoid haemorrhage (SAH) and more specifically of the management of ventilation and sedation therapy (VST) in the ... -
Unterschiede und Gemeinsamkeiten der bioethischen Diskussion über das Hirntodkonzept in der Bundesrepublik Deutschland und in der Volksrepublik China
(2015-03-24)Developments in the field of medicine often lead to an adjustment of the boundary between the concepts of life and death. Recent scandals surrounding the allocation of donor organs are intensifying discussions about the ... -
Unterschiedliche Aktivierung von Signalwegen zur Zellproliferation in mesenchymalen Tumoren des Gastrointestinaltrakts
(2010-06-09)AIMS:The tumor-initiating events in GISTs are activating mutations in the receptor tyrosin kinases KIT und PDGFRA. In contrast, little is known about tumor initiation in true leiomyogenal ... -
Untersuchung arbeitsbezogener Endpunkte in randomisierten, kontrollierten Studien zur Behandlung chronischer Schmerzerkrankungen
(2016-07-08)Chronic painful conditions have a significant impact on ability to work. This systematic review aims at analysing work-related outcomes in randomised placebo-controlled trials in chronic painful conditions and painful ... -
Untersuchung der Auswirkungen einer Trabekulotomie ab interno mittels Trabektom auf den Augeninnendruck - insbesondere beim PEX-Glaukom und Glaucoma chronicum simplex
(2017-07-17)The aim of this study is to evaluate the trabeculotomy by the internal approach with trabectome on patients with glaucoma. It is a retrospective, monocentic study. The following parameters were investigated: intraocular ... -
Eine Untersuchung der Bedeutung des Apoptose-induzierenden Faktors am podozytären Zelltod
(2022-06-17)In this work, the involvement of apoptosis-inducing factor (AIF) in podocyte cell death was investigated in vitro using an established podocyte cell line. For this purpose, a model was used in which the three different ... -
Untersuchung der belastungsabhängigen Adaptation der kardialen Funktion bei Jugendlichen und Erwachsenen mit korrigierter Fallot'scher Tetralogie in der Real Time Magnetresonanz-Tomographie.
(2021-04-09)Background: Correction of Tetralogy of Fallot (cTOF) often results in pulmonary valve pathology and right ventricular (RV) dysfunction. Reduced exercise capacity in cTOF patients cannot be explained by these findings alone. ... -
Untersuchung der Differenzierungskapazität von Osteoblasten und Osteoblastensubpopulationen in vitro und ihre Beeinflussung durch verschiedene Wuchsfaktoren
(2005-09-02)Knowledge of the basic mechanisms controlling osteogenesis and adipogenesis might provide new insights into the prevention of osteoporosis and age-related osteopenia. In this study, ...