Dokumente Fakultät für Biologie und Psychologie (inkl. GAUSS) nach Titel
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Exploring the Functional Relevance of Polymorphisms within the CD14 and IRF-1 Gene for Promoter Activity by Haplotype-Specific Chromatin Immunoprecipitation (HaploChIP)
(2011-02-16)Genetic background may influence susceptibility and progression of various diseases. The IRF-1 promoter polymorphism rs2549009 (G/A) and the variant rs2569190 (C/T) within the CD14 gene ... -
Exploring the roles of RNAPII in genome organization
(2022-12-16)The role of RNAPII in 3D genome organization has been heavily debated over the last two decades. Here, in situ Hi-C and Micro-C data were used to conclusively address this debate. I discovered that: 1) using cell population ... -
Exposition von Proteinen auf der Oberfläche von Escherichia coli Zellen: mechanistische Betrachtung und biotechnologische Anwendung
(2003-12-10)Methods of molecular evolution play an important role for the optimization of biomolecules with respect to function, stability, or interaction. A key aspect is the generation of protein ... -
Expression analysis of Drosophila melanogaster microRNAs
(2007-01-31)miRNAs are tiny regulatory RNAs of 20-25 nucleotides (nt) in length that are endogenously expressed in cells. Hundreds of miRNA genes have been identified in plants and animals. Together they form a large family of regulatory ... -
Expression and function of erythropoietin and its receptor in invertebrate nervous systems
(2010-02-08)This doctoral study provided substantial evidences for the presence of the EPO/EPOR signalling system in the CNS of invertebrates from different phyla (chapter 2) and demonstrated neuroprotective ... -
Expression and function of PSD-93 isoforms in hippocampal synapses
(2010-08-11)Changes in the strength of synaptic transmission are thought to underlie information processing in the brain. At excitatory synapses in the hippocampus, synaptic strength is determined by ... -
Expression and function of serotonin receptor isoforms in the respiratory system
(2005-02-09)A variety of different serotonin receptors (5-HTRs) are known to modify neuronal net-work activity through G-protein activated second messenger pathways. To obtain more information about ... -
Expression and functional analyses of murine Pelota (Pelo) gene
(2007-04-25)In the present study, we have studied the expression pattern of Pelo at the protein level with the help of polyclonal anti-Pelo antibody and generation of conditional inactivation, which ... -
Expression and functional analysis of <i>Tex18</i> and <i>Stra8</i> genes in male germ cells
(2005-11-25)In the present study expression and functional analysis of two testis specific genes, namely Tex18 and Stra8 was performed.RT-PCR, made for the expression analysis of Tex18 gene showed it ... -
Expression and Functional Analysis of the Fas-Associated Factor1 (Faf1) Gene
(2007-04-27)Janchiv, Khulan: Expression and Functional Analysis of the Fas-Associated Factor1 (Faf1) Gene Key words: Faf1, VCP, UBA, UBX, TUNEL Dissertation zur Erlangung des Doktortitels, angenommen ... -
Expression and functional analysis of the germ cell specific genes ADAM 27 and Testase 2
(2004-02-12)In the present study two members of the ADAM family of proteins, murine ADAM 27 and Testase 2, were characterized. Both genes are expressed specifically in the testicular germ cells and therefore are postulated to be ... -
Expression and Functional Analysis of Vsig1 Gene
(2009-05-27)The aims of this study were to determine expression pattern and subcellular localization of VSIG1, a novel member of the immunoglobulin superfamily, and to analyse the function of the Vsig1 ... -
Expression and Regulation of the Insulin-like Growth Factor Axis Components in Rat Liver Myofibroblasts
(2004-11-18)Hepatic stellate cells (HSCs) and liver myofibroblasts (LMFs) represent major cell populations involved in liver fibrogenesis. Several lines of evidence demonstrate that in contrast to LMFs, ... -
Expression der CRFR-Gene in Antwort auf Stress und Lernen
(2003-05-23)Learning can be defined as a process by which organisms alter and adapt their behavior to environmental stimuli thereby forming an inner representation of their world. One of the most ... -
Expression screen for Wnt signaling-like phenotypes identifies Fam132b as a novel inhibitor of BMP signaling in Xenopus
(2014-03-13)The canonical Wnt signaling pathway is known to regulate multiple developmental events,including development of the digestive tract. In this study, we wanted to systematically analyze the role of the Wnt/β-Catenin signaling ... -
Expression und Funktion von Caveolin bei glialen Zellen, insbesondere Oligodendrozyten
(2006-07-25)Caveolin-containing microdomains (CMD) are subdomains of the plasma membrane that contain high concentrations of sphingomyelin, glycosphingolipids and cholesterol. They are involved in ... -
Expression, Charakterisierung und Kristallisation der spleißosomalen Proteine SMNrp, U4/U6-60k und U4/U6-90k
(2006-01-20)The U4/U6-20k/60k/90k-complex, a component of the U4/U6*U5-snRNP-complex, and SMNrp are involved in the assembly of the human spliceosome. It was suggested that the recruiting of the ... -
Expressionsanalyse des humanen Histonsubtyps H1x
(2008-06-02)Nuclear eukaryotic DNA is organised as chromatin in conjunction with proteins. The basal structural organisation unit of chromatin is the nucleosome consisting of the nucleosome core particle, ... -
Extinctions in complex food webs: drivers and consequences
(2013-09-04)Biodiversity is declining rapidly throughout the world. The rate of extinctions matches historical extinction waves and is likely to accelerate even further since two main drivers of biodiversity loss, global warming and ... -
Extracellular vesicle release of α-Synuclein is mediated by SUMOylation
(2015-11-13)We hypothesized that cells release and transfer α-Syn associated with EVs, followed by highly efficient internalization and induction of α-Syn aggregation in previously healthy neurons. EVs of 40-100 nm diameter can either ...