Dokumente Fakultät für Biologie und Psychologie (inkl. GAUSS) nach Titel
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Role of Smad-interacting Protein 1 (Sip1/Zfhx1b) in the development of the cerebral cortex
(2006-05-19)Smad-interacting protein 1 (Sip1/Zfhx1b) is a transcription factor that has been previously implicated in TGF-β/BMP signaling and in the etiology of the Mowat-Wilson syndrome. The expression ... -
Role of the CD40 receptor/CD154 ligand dyad in the control of smooth muscle cells phenotype
(2003-12-18)In the pathogenesis of atherosclerosis, circulating leukocytes adhere to endothelial cells, migrate through them and enter the vessel wall. CD40, a member of the tumor necrosis factor ... -
Role of the different domains of PSD-95 in basal synaptic transmission
(2011-11-09)Learning and memory has been postulated to rely on changes in synaptic transmission strength. At excitatory synapses in the hippocampus CA1 region, synaptic strength is mainly regulated by ... -
Role of the mGRIP1 homologue DGrip in the Drosophila neuromuscular system
(2005-07-05)Here, the identification and characterisation of the Drosophila homologue of the Glutamate Receptor Interacting Protein, DGrip is described. Mutants of DGrip show four scorable defects, a ... -
Role of the microtubulin-associated molecule tau in inflammatory-mediated axonal damage
(2008-02-14)Intracellular aggregates of the microtubule associated protein tau in neurites are the major component of neurofibrillary tangles in Alzheimer's disease and other neurodegenerative tauopathies. The exact molecular mechanism of ... -
Role of transport systems in cortisol release from human adrenal cells
(2004-05-25)Adrenal steroid hormones (e.g., cortisol) play a pivotal role in the regulation and maintenance of metabolic homeostasis. The secretion of glucocorticoids from adrenocortical cells into ... -
Roles of the Cpc1 regulator of the cross-pathway control in the Verticillium plant pathogens
(2014-06-20)Verticillium longisporum is a soil-borne fungal pathogen of oilseed rape (Brassica napus). Infection is initiated by hyphae from germinating microsclerotia which invade the plant vascular system through penetration of the ... -
Die Rolle der beiden Transkriptionsfaktoren AtbZIP1 und AtbZIP53 aus Arabidopsis thaliana in der Anpassung des pflanzlichen Metabolismus an Energiemangelbedingungen
(2011-02-11)Energy deprivation, induced for example by long periods of darkness, leads to dramatic reprogramming of the plant's metabolism. Macromolecules like proteins, amino acids, fatty acids, ... -
Die Rolle der IGF-Achse in Kombination mit anderen Wachstumsfaktor-Signalwegen bei der Resistenz oder dem Ansprechen von kolorektalen Karzinomen auf eine Radiochemotherapie
(2013-10-11)In the Western world cancer represents one of the major health problems. Colorectal cancer (CRC) is the third most common tumor incidence. In advanced disease, in most cases a combined radiochemotherapy (RCT) is performed, ... -
Die Rolle der Synaptische Kurzzeitplastizität im neuronale Schaltkreise
(2010-12-03)Neuronal microcircuit is built by neurons connected with dynamic synapses. Short-term synaptic plasticity is one form of the synaptic dynamics, which plays various roles in the circuit ... -
Die Rolle des IKK/NF-kappaB Signalweges bei der Myelinisierung, De- und Remyelinisierung des zentralen Nervensystems
(2008-08-27)The present thesis aimed to elucidate the function of the classical NF-kappaB pathway in development (myelination), damage (demyelination) and regeneration (remyelination) of myelin sheaths ... -
Rolle von löslichen MHC-Klasse I-Molekülen bei der Apoptose sensibilisierter T-Lymphozyten
(2003-06-27)Dendritic cells (DC) are the most potent antigen-presenting cells and may be possible candidates in the immune therapy because of their ability to induce a primary T-cell-dependent immune ... -
Die Rolle von Phosphoinositiden bei der Auxinsignalleitung von Arabidopsis thaliana
(2013-05-28)The influence of the phosphoinositide network on auxin-signaling in Arabidopsis thaliana The phytohormone auxin (IAA) is a key regulator of growth and organ formation as well as a signal for tropical responses in plants, ... -
Die Rolle von transformierenden Wachstumsfaktoren-beta (TGF-β) in der Entwicklung von Synapsen
(2007-08-07)The transforming growth factors-beta (TGF-β) constitute a super-family of proteins that fulfil various functions during development and differentiation of the nervous system. However, their ... -
Die Rolle von Wnt5a bei der Regression des Basalzellkarzinoms
(2013-01-04)Basal Cell Carcinomas (BCCs) are the most commonly diagnosed tumors among people in the western world. Interestingly, approximately 20% of BCCs show signs of spontaneous regression. Regression of BCCs also occurs in ... -
Root system structure and functions across coastal saltmarsh flooding gradients
(2018-12-04)Salt marshes are ecosystems with extreme environmental conditions such as regular tidal inundation, mechanical disturbances, salinity, waterlogged and anoxic soils, and potentially toxic compounds in the soil. This adverse ... -
Roots of Primate Cognition. The Primate Cognition Test Battery applied to three species of lemurs (Varecia variegata, Lemur catta and Microcebus murinus).
(2018-05-16)Compared to other mammals, primates have evolved relatively large brains and outstanding cognitive skills. Given that brain tissue is energetically very costly, one major evolutionary question concerns possible selection ... -
Der Rotmilan (Milvus milvus) im Unteren Eichsfeld.
(2013-11-19)In the present study were examined population density, habitat use and composition, young bird rearing, food and predation on Red Kite (Milvus milvus). Essential questions were how stable is the stock in the area and what ... -
Röntgenstrahlen induzierte DNA- Doppelstrangbrüche in säugen Zellen in Abhängigkeit vom Zellzyklus.
(2002-11-25)The present study reports improvements in the neutral comet assay first introduced by (Singh and Stephans, 1997; Olive et al., 1998) to measure radiation induced DNA damage. Different ... -
Ryanodine receptors in experimental autoimmune encephalomyelitis, an animal model of multiple sclerosis
(2015-10-19)The activation of auto-aggressive T cells is crucial for the development of autoimmune diseases, such as multiple sclerosis (MS) or its animal model experimental autoimmune encephalomyelitis (EAE). T cell activation relies ...