Dokumente Fakultät für Biologie und Psychologie (inkl. GAUSS) nach Titel
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Neuroligins Determine Synapse Maturation and Function
(2007-07-10)This project investigated the role of neuroligins in brainstem respiratory network of NL 1-3 and NL 2 conventional knockout mice. The deletion of all three neuroligin genes leaded to a ... -
Neuromuscular adaptations induced by long-term motor skill training
(2020-11-05)This thesis addresses the question of whether spinal cord’s monosynaptic circuitry can be altered due to long-term motor skill acquisition. We researched functional organization and skill-related adaptation in muscle spindle ... -
Neuronal and Perceptual Effects of Selective Attention in the Primate Visual System
(2010-07-21)The work included in this thesis examines cognitive influences on the processing of visual information both on the neural and the behavioral level. A prominent mechanism for the ... -
Neuronale Grundlagen appetitiven und konsumatorischen Verhaltens: Die Funktion des Neuropeptids SIFamid bei Drosophila melanogaster
(2013-09-18)Feeding behavior is crucial for survival of animals and a partial aspect of a homeostatic process. Appetitive and consumption behavior are induced by innate and motivational conditions. Satiated and unsatiated states depend ... -
Neuroplasticity: induction and modulation by external stimulation and pharmacological intervention
(2007-08-16)Neuroplasticity, the ability of the human brain to reorganize itself structurally and/or functionally, has been intensively studied in modern neuroscience research. The recent development ... -
Neuroprotektion und Neurorestauration im MPTP Modell der Parkinson Erkrankung
(2010-07-01)Parkinson s disease (PD) is the most common neurodegenerative movement disorder of the basal ganglia and is characterized by a progressive loss of dopaminergic neurons in the substantia ... -
Neuropsychologische Testleistungen bei Patienten mit Koronarer Herzkrankheit und ihr Zusammenhang mit morphologischen Auffälligkeiten im cranialen Kernspintomogramm
(2003-03-05)Recent studies using structural MRI show more lacunar lesions and more white matter changes in patients with coronary artery disease. Cognitive decline has also been shown in these patients. ... -
Neuropsychologische Testleistungen, Hippocampus-Volumina und Stressverarbeitungsstrategien bei traumatisierten Probanden in Abhängigkeit vom Vorliegen einer Posttraumatischen Belastungsstörung
(2004-02-11)In recent studies, subjects with post traumatic stress disorders (PTSD) have been found with more cognitive deficits and smaller hippocampal volumes in comparison to traumatized subjects ... -
Neuropsychologische Testleistungen, psychopathologische Symptomatik und Hippocampusvolumen bei psychisch traumatisierten Patientinnen
(2003-05-26)Individuals having experienced childhood physical or sexual abuse frequently present with a range of psychiatric symptoms and disorders. Recently it has been shown that persons having ... -
New fatty acids, oxylipins and volatiles in microalgae
(2007-11-26)The main objective of the present thesis was the identification of microalgae producing compounds of high value, in particular polyunsaturated fatty acids (PUFAs) and oxylipins which might ... -
New molecular technologies to improve the Sterile Insect Technique for the Mediterranean fruitfly <i>Ceratitis capitata</i> (Diptera; Tephritidae)
(2008-05-26)Insect pests cause enormous economic losses to livestock as well as pre- and postharvest stages of agricultural commodities. The Mediterranean fruit fly Ceratitis capitata (medfly; Wiedemann, Diptera: Tephritidae;) is one ... -
NF-ĸB mediated signaling mechanisms in epidermal homeostasis and carcinogenesis
(2013-09-16)The transcription factor NF-κB is a major player in a wide variety of crucial cellular functions such as proliferation, apoptosis, invasion as well as inflammation. However in the human epidermis, opposite, growth inhibitory ... -
Niche differentiation of two sympatric colobines, Simias concolor and Presbytis potenziani on the Mentawai Island of Siberut, Indonesia
(2012-12-17)Colobines or leaf eating monkeys are characterized by a specialized digestive system and hence, rather specialized dietary requirements. Therefore, the resulting competition over suitable food would favor a parapatric ... -
NMR Spectroscopic studies of calmodulin plasticity in calcium signalling
(2008-03-18)The present work focused both in structural and dynamic studies on the ubiquitous Ca2+ signaling protein calmodulin. Calmodulin has been extensively studied both for its biological importance in the regulation of its ... -
No sex, No problem? Mutation accumulation in asexual animals
(2020-07-03)According to classical predictions, sex is beneficial because it allows for purging of slightly deleterious mutations via effective purifying selection. In asexual organisms mutational load increases over time, eventually ... -
Non-human primate iPS cells for cell replacement therapies and human cardiovascular disease modeling
(2019-12-03)Induced pluripotent stem cells (iPSC) have revolutionized biomedical research due to their versatility. They have potential for regenerative medicine, drug testing, disease modeling and developmental biology. The development ... -
NOVEL APPROACHES TO MODELING AND TREATMENT OF COGNITIVE DEFICITS IN NEUROPSYCHIATRIC DISEASES
(2010-10-15)Cognitive deficits and impairments of higher brain functions are the most burdening features in various neuropsychiatric disorders (e.g. Elvevag and Goldberg, 2000). Up to now, there are ... -
Novel Insights in Structure and Mechanism of Escherichia coli Transketolase
(2018-05-18)Thiamine diphosphate (ThDP) dependent enzymes fulfill a number of indispensable functions in metabolism. Further, they are well-researched work-horses of biotechnology. Thus, deepening of our mechanistic and structural ... -
Novel insights into speech production networks of adults with developmental stuttering as revealed by analyses of speech intention, syllable frequency, and long-term therapy effects
(2021-02-25)Stuttering leads to involuntary disruptions of the speech flow. Stuttering is thought to emerge due to impaired speech planning, initiation, sensorimotor integration or inhibition of speech segments. Previous research has ... -
Novel interaction partners of the chromatin remodeler CHD7, a protein mutated in CHARGE syndrome
(2012-09-14)Summary CHARGE syndrome, an autosomal dominant inherited multiple malformation syndrome is caused by mutations in the chromodomain helicase DNA binding protein 7 gene (CHD7). In 10% of ‘typical’ CHARGE patients and 40-50% ...