Human- und Zahnmedizin: Recent submissions
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Effekte der transkutanen Vagusnervstimulation auf kardiovaskuläre und autonome Parameter
(2024-02-05)Background: Different diseases, including cardiovascular and inflammatory diseases, are associated with a shift in sympathovagal balance in the sympathetic direction. Invasive vagus nerve stimulation is a treatment method ... -
Langzeit-EIT-Monitoring als Indikator für die Entstehung eines Lungenödems während maschineller Beatmung im Tierexperiment
(2024-02-02)In the present study, the question of the extent to which long-term EIT monitoring (EIT = electrical impedance tomography) is suitable as an indicator for the development of pulmonary oedema during mechanical VILI ventilation ... -
Detektion diagnostischer Frühmarker der Nierenfibrose im Urin von Patienten mit Alport-Syndrom mittels proteomischer Methoden
(2024-02-02)Detection of early diagnostic tools of kidney sclerosis in the urine of patients with Alport-Syndrome using proteomic methods. -
Einfluss von Bluttransfusionen auf das Outcome von Patienten mit Sepsis
(2024-01-29)Despite modern medical care, sepsis remains an issue, especially for the aging society with an increasing number of multimorbid patients. The group of sepsis patients shows large heterogeneity and there are numerous factors ... -
Kalziumhandling und Kalziumpufferung bei familiärer dilatativer Kardiomyopathie am Modell der induzierten pluripotenten Stammzellen
(2024-01-29)Dilated cardiomyopathy (DCM) is a heterogeneous disease characterised by left ventricular dilatation and a reduced ejection fraction. In addition to progressive left heart failure, the poor clinical prognosis is primarily ... -
PFKFB3-Inhibition während einer Radiochemotherapie des Rektumkarzinoms – Überprüfung in einem patient-derived xenograft In-vivo-Modell
(2024-01-29)Colorectal cancer (CRC) is the third most common cancer diagnosed worldwide and the second leading cause of cancer death. Approximately 30% of colorectal carcinomas are localized in the rectum. Neoadjuvant radiotherapy ... -
Digitalisierung der Klinik für Unfallchirurgie, Orthopädie und plastische Chirurgie
(2024-01-26)Clinical relevanceThe increasing digitalization is a process that can be observed worldwide and extends over many different areas. In the healthcare sector, too, innovations are researched, developed and tested that ...
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Ablationsbehandlung epikardialer akzessorischer Leitungsbahnen über das Koronarvenensystem bei Kindern und Jugendlichen
(2024-01-24)This retrospective data analysis was used to collect data from 24 patients ≤ 18 years who underwent ablation treatment of accessory pathways within the coronary venous system in Göttingen between October 2002 and December ... -
Influence of Age at Onset and Obesity on Pediatric Multiple Sclerosis
(2024-01-19)Pediatric multiple sclerosis has many parallels to adult multiple sclerosis, however, the initial disease course is generally associated with more relapses yet better recovery and slower disability progression than in ... -
Schlafbeschwerden bei Depressionen und Bipolarer Störung im Therapieverlauf unter intermittierender Theta-Burst-Stimulation oder medikamentöser Behandlung
(2024-01-17)A total of 73 test subjects in a depressive phase were compared over 5 weeks for changes in their sleep complaints over the course of different therapies: 38 subjects received intermittent theta burst stimulation and 35 ... -
The effect of Natalizumab on functional properties of monocytes in patients with Multiple Sclerosis
(2024-01-12)Natalizumab (NTZ), a monoclonal antibody against very late antigen-4 (VLA-4), is one of the most efficient therapies to prevent acute relapses in multiple sclerosis (MS). Since VLA-4 is a vital adhesion molecule for ... -
Außermedizinische Wünsche am Lebensende von schwer erkrankten Menschen
(2024-01-08)The topic of wishes at the end of life is widely discussed in the media, but mostly limited to aspects of medical treatment at the end of life (e. g. living wills, organ donor cards). For palliative care, the holistic view ... -
Einfluss von Lebensmittelfotos mit unterschiedlicher Makronährstoff-Zusammensetzung auf die Serum-Ghrelin-Konzentration
(2024-01-05)Ghrelin is the only hormone with an orexigenic effect. Serum concentrations fluctuate periodically in anticipation of food intake: shortly before the upcoming meal they increase and are suppressed postprandially. The peptide ... -
Anti-Aging-Forschung: Technikbewertung und ethische Implikationen am Beispiel der Hormontherapie und Telomerenforschung
(2024-01-04)Numerous options for intervening in the aging process have been scientifically investigated in recent decades and are still being researched today. There are also a variety of external and internal applications and products ... -
Langzeitergebnisse eines interventionellen Vorhofohrverschlusses durch einen AMPLATZER-LAA-Okkluder in einem Hochrisikokollektiv
(2024-01-04)LAA occlusion with the Amplatzer devices - long term outcomes in a high-risk cohort LAA ooclusion is a favorable therapeutic option in patients with atrial fibrillation and contra-indications for oral anticoagulation ... -
Zahnärztliche Diagnostik und Versorgung von Demenzpatient*innen in non-Compliance-Situationen
(2024-01-03)The aim of this dissertation is to use a descriptive questionnaire study to show how dentists and nursing staff assess the refusal attitudes of patients with dementia in treatment and care situations and what the level of ... -
Klinische Bewährung computergestützt gefertigter Teilkronen aus einer zirkonoxidverstärkten Lithiumsilikat-Keramik nach einer Beobachtungszeit von 5 Jahren
(2024-01-03)Objectives: Prospective practice-based clinical evaluation of chairside-fabricated ceramic partial crowns (CCPCs) made from a glaze-fired zirconia-reinforced lithium silicate (ZLS) ceramic (Celtra Duo, Dentsply Sirona, ... -
Dokumentation von Ethik-Fallberatungen
(2023-12-21)Over the last two decades clinical ethics have become increasingly more important. A central task of clinical ethics are ethics case consultations. The “Akademie für Ethik in der Medizin” (a German professional society for ... -
Molekulare und elektrophysiologische Untersuchung der Exozytose in der Maus-Cochlea
(2023-12-20)The afferent synapses between inner hair cells (IHC) and spiral ganglion neurons are specialized to faithfully encode sound with sub-millisecond precision over prolonged periods of time. Here, I studied the role of Rab3 ... -
Inzidenz und prädiktive Faktoren des bilateralen papillären Schilddrüsenkarzinoms
(2023-12-20)Papillary thyroid carcinoma is showing an increasing incidence worldwide, not least due to improved diagnostic options. Papillary microcarcinoma, which is defined as a papillary thyroid carcinoma with a tumor size ≤10 mm, ...