Dokumente Human- und Zahnmedizin nach Erscheinungsdatum
Anzeige 1-20 von 3410
-
EZM-Recycling als Remodelingmechanismus des plastischen Gehirns
(2026-01-21)Although long understudied, the neural extracellular matrix (ECM) has emerged as a key regulator of synaptic function and plasticity in research conducted over the past two decades. This development has led to the expansion ... -
Quantifizierung von Sehverzerrungen (Metamorphopsie): Eine prospektive vergleichende Studie zwischen Metamorphopsie Detektor und M-Charts
(2026-01-21)Background: Metamorphopsia is a key symptom of macular disorders, yet standardized quantitative methods for detection are lacking. This prospective study compares AMD® (web-based) and M-Charts regarding correlation, ... -
Untersuchung der Plastizitätsveränderung im Motorcortex durch Manipulation der Direktionalität und Pulsbreite bei hochfrequenter transkranieller Magnetstimulation mit einem cTMS-Gerät: Eine mehrfaktorielle Varianzanalyse
(2026-01-21)This work investigates how the directionality and pulse width of high‑frequency cTMS pulses influence plasticity in the human motor cortex. In a 10‑Hz rTMS study with 15 healthy participants, four cTMS pulse types were ... -
Der therapeutische Effekt von Rutin als Antioxidans und Proteindisulfidisomeraseinhibitor auf renale Fibrose
(2026-01-21)Chronic kidney disease (CKD) is a major health condition with a substantial impact on global mortality and morbidity. Pathophysiological, CKD culminates in renal fibrosis due to accumulation of extracellular matrix. ... -
Evaluation der Inanspruchnahme von komplementärmedizinischen Maßnahmen bei hämatologischen Patient*innen im Vergleich zu onkologischen in einem ambulanten Patient*innenkollektiv
(2026-01-21)The acceptance and use of complementary and alternative medicine (CAM) is very high in Germany compared to other countries. Many cancer patients seek alternative treatments to complement conventional tumour therapy, often ... -
Der Effekt statischer Magnetfelder auf die Erregbarkeit der Hirnrinde bei Patient*innen mit amyotropher Lateralsklerose
(2026-01-20)Amyotrophic lateral sclerosis (ALS) is a rare, complex, and progressive neurological disorder that on average leads to death within two to four years after diagnosis. To date, only a limited number of therapeutic options ... -
Die nukleare Translokation des Kalziumbindenden-Proteins Calbindin-1 und dessen Rolle bei der Kalziumhomöostase in den distalen Tubuluszellen der Niere.
(2026-01-16)The nuclear translocation of the calcium binding protein calbindin-1 and its role in the calcium-homeostasis in kidney distal tubule cells Calcium (Ca2+) plays a key role in many physiological processes like hormone ... -
Analyse der Aktivitäten verschiedener Gerinnungsfaktoren im Verlauf unter einer venovenösen extrakorporalen Membranoxygenierung
(2026-01-16)Acute respiratory distress syndrom (ARDS) can lead to severe acute hypoxemic respiratory failure. When conventional management strategies failed veno-venous extracoporeal membrane oxygenation (vvECMO) can be a rescue ... -
Ergebnisse mikroskopischer und röntgenologischer Untersuchungen zur Differentialdiagnose von Krankheitsspuren an ausgewählten Skeletproben der frühbyzantinischen Kinderpopulation vom Arslantepe/Malatya (Türkei)
(2026-01-16)This study shows that the microscopic analysis of bone samples can provide reliable diagnoses of disease burdens. In this case, the analysis was used to study an early Byzantine child population in southern Central ... -
Effect of microglia depletion on white and gray matter inflammation in myelin mutant mice
(2026-01-16)This thesis aimed to characterize microglia phenotype following CSF1R inhibitor PLX5622 treatment in the catatonia mouse model Cnp knockout (Cnp-/-). Prior research established Cnp-/- mice as a translational model for ... -
Liefern kapilläre Blutentnahmen, die über Postversand ins Labor verschickt wurden, vergleichbare Messergebnisse gegenüber Laboranalysen aus venösen Blutentnahmen in der Hausarztpraxis?
(2026-01-15)Introduction: New upper-arm devices allow patients to collect capillary self-blood samples on their own. Thanks to improved laboratory measurement technologies in recent decades, much smaller sample volumes are now required, ... -
Lipidhomöostase und deren Maladaptation im zentralen Nervensystem
(2026-01-14)Multiple sclerosis is an autoimmune, demyelinating disease that is highly relevant in terms of both its prevalence and its socioeconomic significance. Pathophysiologically, there is a complex, dynamic interaction between ... -
Retrospektive Analyse lasergestützter Kalkulationen von Intraokularlinsen mittels unterschiedlicher Berechnungsformeln
(2026-01-14)Background: The calculation of the refractive power of the intraocular lens (IOL) to be implanted is a crucial step in cataract surgeries. Various formulas that utilize different biometric parameters are available. ... -
Studie zum klinischen Outcome von Patienten nach Wirbelkörperersatz an der ventralen Brust- und Lendenwirbelsäule
(2026-01-13)This retrospective study evaluates long-term outcomes after anterior vertebral body replacement with bisegmental fusion in 76 patients with lower thoracic and lumbar spine fractures. No significant differences were found ... -
Multimorbidität als Prädiktor für eine stationäre Aufnahme in der klinischen Notfall- und Akutmedizin
(2026-01-08)Background Parallel to demographic trends, an increase of multimorbid patients in emergency and acute medicine is prominent. To define easily applicable criteria for the necessity of inpatient admission, a hierarchical ... -
Eine randomisierte, verblindete, placebokontrollierte prä-klinische Studie zur antifibrotischen und nephroprotektiven Wirkung einer Kombinationstherapie mit dem monoklonalen Antikörper Actinab und dem ACE-Inhibitor Ramipril am Alport-Mausmodell
(2026-01-08)Alport syndrome is a hereditary disorder of type IV collagen that leads to impaired glomerular filtration function in the kidneys. The current standard treatment is early administration of an ACE inhibitor. In this study, ... -
Durchführbarkeit und Wirksamkeit eines kollaborativen Behandlungsansatzes in der Sekundärprävention der Koronaren Herzerkrankung
(2026-01-06)Adequate management of cardiovascular risk factors (RFs) is important in the secondary prevention of coronary heart disease (CHD), but in practice it is often not easy to achieve. In the USA, the blended collaborative care ... -
Validierung einer deutschen Version des Central Sensitization Inventory (CSI-GE)
(2026-01-06)Central sensitization is considered an important factor in the development and maintenance of various chronic pain syndromes. Quantifying this process is challenging. The Central Sensitization Inventory (CSI) was developed ... -
Einfluss der Aminosäure Phenylalanin an Position 244 des organischen Kationentransporters OCT1 auf die Transportaktivität
(2026-01-06)Membrane transporter proteins such as OCT1 from the SLC family are important for the distribution and homeostasis of drugs and endogenous substances in tissues. OCT1 is known for its polyspecificity, transporting at least ... -
Häufigkeit der intra- und frühen postoperativen Blutungskomplikationen bei Glaukomoperationen in Abhängigkeit von gerinnungshemmenden Substanzen
(2026-01-06)With the increasing age of the population, the number of patients requiring ophthalmologic care continues to rise. Comorbidities and pre-existing conditions often necessitate treatment with antithrombotic medication, which, ...